Anti-inflammatory, antinociceptive and antioxidant activities of ethanolic extract of Solanum nigrum L. fruits
Joint Authors
al-Fartusi, Adnan Jasim Muhammad
al-Zamili, Awdah M. Yasir
al-Wafi, Haydar A. K.
Source
Iraqi National Journal of Chemistry
Issue
Vol. 2011, Issue 42 (30 Apr. 2011), pp.252-260, 9 p.
Publisher
University of Babylon College of Sciences
Publication Date
2011-04-30
Country of Publication
Iraq
No. of Pages
9
Main Subjects
Topics
Abstract AR
درست فعالية المستخلص الايثانولي لمنقوع نبات عنب الذيب كمضاد للالتهابات و كمسكن للآلام على الجرذان المختبرية، و ذلك بتجريعها فمويا تراكيز مختلفة ،400 100، 200ملغم / كغم من ذلك المستخلص أظهرت الدراسة فعالية معنوية عند الجرعة العالية 400 ملغم/كغم و بفارق معنوي (P < 0.01).
مقارنة مع عقار معروف هو صوديوم دكلوفيناك 50 ملغم/ كغم.
كما تم دراسة الفعالية المضادة للأكسدة للمستخلص الأيثانولي 400 مايكرو غرام/مل إذ أظهر المستخلص فعالية مضادة-و ذلك بأخذ تراكيز مختلفة تراوحت بين 100لأكسدة حامض اللينولينك و قابلية اختزال قويه في النظام النموذجي .
Abstract EN
Ethanolic maceration extract of Solanum nigrum L.
fruits belonging to solanaceae family was used.
Anti-inflammatory activity of the extract was examined using carrageenan induced paw edema and xylene induced ear edema in mice.
Antinociceptive activity was studied using the hot plate and writhing tests.
The study was carried out using doses of 100, 200 and 400 mg / kg orally.
The extract showed significant anti-inflammatory and antinociceptive activity at the dose of 400 mg / kg (P < 0.01) as compared to standard drug Diclofenac sodium (50 mg / kg).
Antioxidant and reducing power activities were evaluated using different concentration (100-400 μg / mL) of ethanol extract.
The extract had the most potent antioxidant effect toward linoleic acid model system, and strong reducing power ability.
American Psychological Association (APA)
al-Fartusi, Adnan Jasim Muhammad& al-Wafi, Haydar A. K.& al-Zamili, Awdah M. Yasir. 2011. Anti-inflammatory, antinociceptive and antioxidant activities of ethanolic extract of Solanum nigrum L. fruits. Iraqi National Journal of Chemistry،Vol. 2011, no. 42, pp.252-260.
https://search.emarefa.net/detail/BIM-405940
Modern Language Association (MLA)
al-Fartusi, Adnan Jasim Muhammad…[et al.]. Anti-inflammatory, antinociceptive and antioxidant activities of ethanolic extract of Solanum nigrum L. fruits. Iraqi National Journal of Chemistry No. 42 (2011), pp.252-260.
https://search.emarefa.net/detail/BIM-405940
American Medical Association (AMA)
al-Fartusi, Adnan Jasim Muhammad& al-Wafi, Haydar A. K.& al-Zamili, Awdah M. Yasir. Anti-inflammatory, antinociceptive and antioxidant activities of ethanolic extract of Solanum nigrum L. fruits. Iraqi National Journal of Chemistry. 2011. Vol. 2011, no. 42, pp.252-260.
https://search.emarefa.net/detail/BIM-405940
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 259-260
Record ID
BIM-405940
